The Waiting Game: Exploring the Two-Week Wait After IVF

Following an embryo transfer during in vitro fertilization (IVF), patients enter the Two-Week Wait (TWW)—a fourteen-day period prior to taking a pregnancy test. This two-week window is often characterized by feelings of anticipation and suspense as individuals wait to see if the process has succeeded.

In my practice, I’ve seen many patients struggle to navigate this period, making it one of the more emotionally taxing moments of the IVF experience. That being said, the TWW involves several physical changes and important decisions, each of which can mark key turning points in your pursuit of fertility care.

This post will cover all you can expect during your TWW. Hopefully, this overview can remove some stress from the process and help guide your decision making during this time. If you have any concerns about your TWW, bring them up with your doctor. After all, while the TWW is certainly a suspenseful time, it doesn’t have to be a negative experience. You can make this among the most hopeful sequences of your entire IVF treatment through careful management and attention to your body.

Understanding the Two-Week Wait

During the TWW, patients experience an implantation window, a process in which a fertilized embryo travels down the fallopian tube and attaches itself to the lining of the uterus. Hormonal changes—significantly, an increase in progesterone—play a vital role in preparing the body for a potential pregnancy. These changes create an environment that supports the growth of the embryo.

While physical symptoms may manifest during the TWW, it is essential to note that these can vary widely among individuals. Some common symptoms that individuals may experience include fatigue, breast tenderness, and cramping. However, these symptoms are not definitive indicators of pregnancy. Keep in mind that being pregnant without experiencing these symptoms is also possible.

During the TWW, individuals might experience various emotions, from anticipation to anxiety and hope. Most of these feelings relate to a sense of uncertainty, as you may not experience any apparent indicators of pregnancy during this time. I recommend maintaining realistic expectations throughout. The data shows that IVF is a safe and effective means of achieving conception, though its success rate does vary based on several factors, including the age of the patient. Focus on any changes to your body, and maintain an open line of communication with your doctor. Most of all, remember that every IVF patient experiences the same range of feelings during the TWW—so you’re not alone.

To Test or Not to Test

During the TWW, you may feel an urge to take a pregnancy test as a means of detecting pregnancy early. Taking a home pregnancy test can give IVF patients a sense of empowerment or control during this challenging phase. That being said, keep in mind that these pregnancy tests can generate confusing or incorrect results—false positives or negatives. If you test too early, you may get an inaccurate reading due to insufficient levels of the pregnancy hormone hCG. 

Although some tests make claims of early detection, experts generally recommend waiting until ten to fourteen days after the embryo transfer to gain reliable results. Rather than relying on pregnancy tests to alleviate anxiety during this phase, direct your attention toward stress management and engage your healthcare provider. 

Embracing Your Two-Week Wait

The Two-Week Wait can be one of the most challenging times during the IVF experience. While monitoring changes to your body during this fourteen-day window, you may undergo feelings of suspense or anxiety as you wait to see if you have achieved a successful conception. Keep in mind that individuals can be pregnant without showing any of the significant physical indicators. Likewise, be wary of taking home pregnancy test results, especially early in the TWW, because those tests may provide false positives or negatives.


Instead, lean on healthcare experts like our staff at Nevada Fertility Institute. With the guidance of IVF specialists, you can ensure that you navigate the TWW as safely and smoothly as possible. You can better chart a course through support and resilience during this crucial phase of your fertility journey.

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Lifestyle Factors Affecting Fertility

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Egg Retrieval Unveiled: A Comprehensive Guide to the IVF Stimulation Phase